Finkelstein Eric A, Troped Philip J, Will Julie C, Palombo Ruth
RTI, Health, Social and Economics Research, Research Triangle Park, North Carolina 27709, USA.
J Womens Health Gend Based Med. 2002 Jul-Aug;11(6):519-26. doi: 10.1089/152460902760277877.
The Massachusetts WISEWOMAN Project is a cardiovascular disease (CVD) risk reduction program targeting older uninsured and underinsured women. The cost-effectiveness of providing CVD screening and enhanced lifestyle interventions (EI), compared with providing CVD screening and a minimum intervention (MI), was assessed at five El and six MI healthcare sites.
Cost calculations were based on data collected during screenings and intervention activities conducted with 1586 women in 1996. Risk factor data, including cholesterol and blood pressure measures, were used to create a summary effectiveness outcome, the 10-year probability of developing coronary heart disease (CHD). The cost-effectiveness ratio of the EI, compared with the MI, was calculated by dividing the incremental cost of the EI by the incremental effectiveness of the EI.
The incremental cost of the EI was $191. During the 1-year study period, the 10-year probability of CHD decreased from 9.4% to 9.2% in the MI group and from 10.3% to 9.8%in the El group. Based on these results, it would cost $637 to achieve a 1 percentage point larger decrease in the 10-year probability of CHD for women enrolled in the El. However, because differences between groups were not statistically significant, we cannot reject the hypothesis that the El results in no greater reductions in CHD risk.
Although women enrolled in both the MI and El showed decreases in CHD risk during the study period, future research is needed to assess the impact of lifestyle interventions targeting financially disadvantaged women.
马萨诸塞州明智女性项目是一项降低心血管疾病(CVD)风险的项目,目标人群为未参保和参保不足的老年女性。在五个强化生活方式干预(EI)医疗站点和六个最低干预(MI)医疗站点,对提供CVD筛查和强化生活方式干预与提供CVD筛查和最低干预相比的成本效益进行了评估。
成本计算基于1996年对1586名女性进行筛查和干预活动期间收集的数据。包括胆固醇和血压测量在内的风险因素数据用于创建一个综合有效性结果,即患冠心病(CHD)的10年概率。EI与MI相比的成本效益比通过将EI的增量成本除以EI的增量有效性来计算。
EI的增量成本为191美元。在为期1年的研究期间,MI组患CHD的10年概率从9.4%降至9.2%,EI组从10.3%降至9.8%。基于这些结果,对于参加EI的女性,要使患CHD的10年概率再降低1个百分点,将花费637美元。然而,由于两组之间的差异无统计学意义,我们不能拒绝EI不会更大程度降低CHD风险的假设。
尽管参加MI和EI的女性在研究期间CHD风险均有所降低,但仍需要未来的研究来评估针对经济弱势女性的生活方式干预措施的影响。