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透明质烷B凝胶在内镜鼻窦手术后作为伤口敷料的应用。

Use of hylan B gel as a wound dressing after endoscopic sinus surgery.

作者信息

Frenkiel Saul, Desrosiers Martin Y, Nachtigal Dan

机构信息

Department of Otolaryngology, McGill University, Montreal, Quebec.

出版信息

J Otolaryngol. 2002 Aug;31 Suppl 1:S41-4. doi: 10.2310/7070.2002.21296.

DOI:10.2310/7070.2002.21296
PMID:12243243
Abstract

Although serious sequelae of endoscopic sinus surgery are infrequent, more commonplace surgical management often involves the control of mucosal bleeding. This study was conducted to assess the efficacy of an elastoviscous hylan gel as a postsurgical wound dressing for promotion of hemostasis. Twenty patients with a diagnosis of chronic sinusitis were evaluated. In randomized fashion, the gel dressing was placed into one operated cavity while the contralateral side served as the control. The results indicated that hylan gel was effective in stilling postsurgical bleeding, particularly in the fulminant polyposis cases who had a larger and more exposed cavity. These early results indicate a potential benefit of a gel dressing for hemostasis when used at the conclusion of the operative procedure. In addition, other parameters were evaluated in this study, including prevention of postoperative adhesions and the effect on mucosal healing. These parameters showed a positive result compared with the control group.

摘要

尽管内镜鼻窦手术的严重后遗症并不常见,但更常见的手术处理通常涉及控制黏膜出血。本研究旨在评估一种弹性粘性透明质烷凝胶作为促进止血的术后伤口敷料的疗效。对20例诊断为慢性鼻窦炎的患者进行了评估。以随机方式,将凝胶敷料置于一侧手术腔,而对侧作为对照。结果表明,透明质烷凝胶在止住术后出血方面有效,尤其是在腔隙更大且暴露更多的暴发性息肉病病例中。这些早期结果表明,在手术结束时使用凝胶敷料止血有潜在益处。此外,本研究还评估了其他参数,包括预防术后粘连和对黏膜愈合的影响。与对照组相比,这些参数显示出阳性结果。

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Eur Arch Otorhinolaryngol. 2016 Dec;273(12):4061-4071. doi: 10.1007/s00405-015-3863-7. Epub 2015 Dec 26.
2
Steroid-eluting sinus stents for improving symptoms in chronic rhinosinusitis patients undergoing functional endoscopic sinus surgery.用于改善接受功能性内窥镜鼻窦手术的慢性鼻窦炎患者症状的类固醇洗脱鼻窦支架。
Cochrane Database Syst Rev. 2015 Jun 10;2015(6):CD010436. doi: 10.1002/14651858.CD010436.pub2.
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Advances in the surgical management of chronic rhinosinusitis.
慢性鼻-鼻窦炎的外科治疗进展。
Allergy Asthma Clin Immunol. 2005 Mar 15;1(1):21-7. doi: 10.1186/1710-1492-1-1-21.
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[Wound healing after endoscopic sinus surgery and postoperative management].[鼻内镜鼻窦手术后的伤口愈合及术后管理]
HNO. 2009 Aug;57(8):763-71. doi: 10.1007/s00106-009-1938-8.