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[婴幼儿小肠黏膜双糖酶。“正常值”、对数正态分布及年龄依赖性]

[Disaccharidases of the small intestine mucosa in infants and children. "Normal values", log normal distribution and age dependence].

作者信息

Niessen K H, Schmidt K, Brügmann G

出版信息

Z Gastroenterol. 1975 Oct;13(6):565-72.

PMID:1224750
Abstract

In 63 infants and children with a histological normal mucosa of the duodenum, without an isolated defect of enzyme and with a normal increase of xylose and glucose in serum after a combined xylose-lactose loading test the activities of disaccharidases were log normal distributed. The asymmetric distributions were transformed into symmetric ones and the geometric mean (x) as well as the range (+/- 2 s) of maltase, saccharase, isomaltase, lactase and trehalase were calculated. Only the activity of lactase shows a significant dependency on age. In the first year of age the lower limit (x -- 2 s) of this enzyme is much higher than later.

摘要

在63例十二指肠组织学正常的婴幼儿中,无酶的单独缺陷,且在木糖 - 乳糖联合负荷试验后血清木糖和葡萄糖正常升高,双糖酶活性呈对数正态分布。将不对称分布转换为对称分布,并计算麦芽糖酶、蔗糖酶、异麦芽糖酶、乳糖酶和海藻糖酶的几何平均值(x)以及范围(±2s)。只有乳糖酶的活性显示出对年龄有显著依赖性。在1岁时,该酶的下限(x - 2s)比之后要高得多。

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