Vándor E, Simon G, Anda E, Budavári I
Endokrinologie. 1975 Sep;66(1):81-7.
Following 25 mug/day synthetic alpha-MSH administration, the liver regeneration of partially hepatectomized rats proved to be increased. The hormone treatment resulted in an enhanced alanine incorporation of the liver proteins, but this effect was uncertain on partially hepatectomized rats. Due to the hormone treatment the low liver protein content of the operated rats became normal. The pseudocholinesterase activity of the liver homogenate of alpha-MSH treated rats was also elevated. On the basis of these experiments authors are supposing some protein synthesis increasing effect of synthetic alpha-MSH.
每天给予25微克合成α-促黑素细胞激素后，部分肝切除大鼠的肝脏再生被证明有所增强。激素治疗导致肝脏蛋白质中丙氨酸掺入增加，但对部分肝切除大鼠的这种作用尚不确定。由于激素治疗，手术大鼠低水平的肝脏蛋白质含量恢复正常。α-促黑素细胞激素处理大鼠的肝脏匀浆中假性胆碱酯酶活性也升高。基于这些实验，作者推测合成α-促黑素细胞激素有某种增加蛋白质合成的作用。
