鸡胚和蛋黄中的载脂蛋白及脂蛋白家族

Apolipoproteins and lipoprotein families in chicken embryos and egg yolk.

Schjeide O A, Rieffer G, Kelley J L, Alaupovic P

Northern Illinois University, Department of Biological Sciences.

Comp Biochem Physiol B. 1977;58(4):349-52. doi: 10.1016/0305-0491(77)90180-8.

Abstract

Turkey anti-LP-A and anti-LP-B cross react strongly with whole adult chicken serum. 2. Similar reactions occur with whole chicken embryo sera (10-21 days of incubation) and egg yolk fluid. 3. Ultracentrifugation of sera from 14-day old chicken embryos, after reaction with anti-LP-B, reveal complete precipitation of the VLDL and LDL of embryo serum (indicating that adult-type LP-B is the major apolipoprotein of these density classes). 4. All of the chicken embryo adult-type apo-LP-A is in the HDL fraction. 5. However, egg yolk and hen serum VLDL contain apo-LP-A as well as apo-LP-B.

摘要

土耳其抗LP - A和抗LP - B与成年鸡全血清强烈交叉反应。2. 与鸡胚全血清（孵化10 - 21天）和蛋黄液也会发生类似反应。3. 14日龄鸡胚血清与抗LP - B反应后进行超速离心，结果显示胚胎血清中的极低密度脂蛋白（VLDL）和低密度脂蛋白（LDL）完全沉淀（表明成年型LP - B是这些密度级别的主要载脂蛋白）。4. 所有鸡胚成年型载脂蛋白LP - A都存在于高密度脂蛋白（HDL）组分中。5. 然而，蛋黄和母鸡血清中的极低密度脂蛋白既含有载脂蛋白LP - A也含有载脂蛋白LP - B。