Mutalimova A B, Kurdiumova T Iu
Genetika. 1975;11(12):150-1.
The features of dermatoglyphics in 39 children with beta-thalassemia major and in 47 their parents are studied. The control were 70 healthy children. The patients with beta-thalassemia had more often the prevailence of whorls over other finger patterns. There was an increase of the "atd" angle and some increase in the ridge of counts. Parents had also an increase of the amount of whorls, but this increase was less pronounced than under beta-thalassemia. The changes of the dermatoglyphics in parents of children affected with beta-thalassemia major are suggested to ba a phenotypic feature of heterozygous carrier of the mutant gene.
对39名重型β地中海贫血患儿及其47名父母的皮纹特征进行了研究。对照组为70名健康儿童。重型β地中海贫血患者中,斗形纹比其他指纹类型更为常见。“atd”角增大,嵴纹计数略有增加。患儿父母的斗形纹数量也有所增加,但这种增加不如重型β地中海贫血患者明显。重型β地中海贫血患儿父母的皮纹变化被认为是突变基因杂合携带者的一种表型特征。