Whitley R J, Ch'ien L T, Alford C A
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These results suggest that Ara A, within its nontoxic dose range, may be efficacious in the treatment of neonatal HSV infection, provided the drug is given early in the course of the disease. Such studies as this have prompted a large scale multi-institutional study, which hopefully will provide a greater insight into the natural history of this usually devastating disease. The information gathered undoubtedly will lead to better and more specific antiviral agents as well as diagnostic techniques for earlier identification of neonatal HSV disease.
这些结果表明，阿糖腺苷在其无毒剂量范围内，若能在疾病早期给药，可能对新生儿单纯疱疹病毒感染的治疗有效。此类研究促使开展了一项大规模多机构研究，有望更深入地了解这种通常具有毁灭性疾病的自然病程。所收集的信息无疑将催生更好、更具特异性的抗病毒药物以及用于早期识别新生儿单纯疱疹病毒疾病的诊断技术。
