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药物监测仪在麻风病治疗中的潜在用途。

The potential uses of the medication monitor in the treatment of leprosy.

作者信息

Moulding T S

机构信息

National Jewish Hospital, Denver, Colorado 80206.

出版信息

Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):601-6.

PMID:122631
Abstract

A medication monitor has been developed that utilizes radioactive material and photographic film to record the intervals at which patients take medication. In the author's opinion, this equipment represents the most efficient means that has so far become available for determining how regularly outpatients take medication. A monitor for the tuberculosis regimen of isoniazid and thiacetazone has been made at a sufficiently low cost that it is practical to use it in routine treatment programs. An inexpensive system for immediate development of the film that can be used in the most remote locations is also available. Undoubtedly, with appropriate engineering work, a monitor for leprosy regimens could be made. The device has been used with tuberculosis patients and revealed that many patients were grossly irregular in taking their medication. It has been used to oversee medication use by tuberculosis patients and to select those who require either extra attention to improve medication ingestion or completely supervised, directly administered programs. In the treatment of leprosy, it could be used to study new drug regimens, the causes of noncompliance, and for the routine supervision of patients.

摘要

一种药物监测仪已被研发出来,它利用放射性物质和摄影胶片来记录患者服药的时间间隔。在作者看来,这种设备是目前可用于确定门诊患者服药规律程度的最有效手段。一种用于异烟肼和氨硫脲结核病治疗方案的监测仪成本足够低,在常规治疗项目中使用是可行的。还有一种可在最偏远地区使用的、用于胶片即时显影的廉价系统。毫无疑问,通过适当的工程工作,可以制造出用于麻风病治疗方案的监测仪。该设备已用于结核病患者,结果显示许多患者服药极不规律。它已被用于监督结核病患者的用药情况,并挑选出那些需要额外关注以改善药物摄入情况或需要完全监督、直接给药治疗方案的患者。在麻风病治疗中,它可用于研究新的药物治疗方案、不依从的原因以及对患者进行常规监测。

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