Singh G S
Recent Adv Stud Cardiac Struct Metab. 1975;7:401-4.
When frog heart is perfused with high calcium Ringer solution it may be stimulated by a low dose of acetylcholine. This stimulant action is mediated through atropine-sensitive receptors and is blocked by certain calcium antagonists such as local anesthetics, cobalt, magnesium, and phenoxybenzamine. However, the nicotinic action of high doses of acetylcholine on atropinized heart is not blocked by cobalt and magnesium ions.
当用高钙任氏液灌注蛙心时，低剂量的乙酰胆碱可对其产生刺激作用。这种刺激作用是通过对阿托品敏感的受体介导的，并被某些钙拮抗剂如局部麻醉药、钴、镁和酚苄明所阻断。然而，高剂量乙酰胆碱对阿托品化心脏的烟碱样作用不受钴离子和镁离子的阻断。
