夏季月份中乙酰胆碱对阿托品化青蛙心脏的作用。
Action of acetylcholine on the atropinised heart of the frog during summer months.
作者信息
Mediratta P K, Prabhu S, Prasad S, Singh G
出版信息
Indian J Physiol Pharmacol. 1983 Apr-Jun;27(2):161-5.
PMID:6136461
Abstract
During summer months high doses of acetylcholine produced positive inotropic and chronotropic actions in 19 out of 22 preparations of atropinised perfused heart of the frog. Hexamethonium failed to block both the positive inotropic and chronotropic actions of Ach. Interestingly another ganglion blocking agent mecamylamine as well as beta adrenergic blocking agent propranolol blocked the positive inotropic action but not the positive chronotropic action.
摘要
在夏季，高剂量的乙酰胆碱在22个阿托品化的蛙类灌注心脏标本中的19个中产生了正性肌力和正性变时作用。六甲铵未能阻断乙酰胆碱的正性肌力和正性变时作用。有趣的是，另一种神经节阻断剂美加明以及β肾上腺素能阻断剂普萘洛尔阻断了正性肌力作用，但未阻断正性变时作用。
相似文献
1
Action of acetylcholine on the atropinised heart of the frog during summer months.夏季月份中乙酰胆碱对阿托品化青蛙心脏的作用。
Indian J Physiol Pharmacol. 1983 Apr-Jun;27(2):161-5.
2
Action of acetylcholine on the atropinised frog heart during the winter months.冬季乙酰胆碱对阿托品化蛙心的作用。
Indian J Physiol Pharmacol. 1977 Jan-Mar;21(1):66-8.
3
The positive chronotropic effect of acetylcholine has muscarinic and nicotinic components in the neonatal rat heart.乙酰胆碱对新生大鼠心脏的正性变时作用具有毒蕈碱样和烟碱样成分。
J Pharmacol Exp Ther. 1988 Nov;247(2):585-9.
4
Muscarinic suppression of the nicotinic action of acetylcholine on the isolated, blood-perfused atrium of the dog.毒蕈碱对乙酰胆碱在犬离体血液灌注心房上烟碱样作用的抑制。
Naunyn Schmiedebergs Arch Pharmacol. 1975;289(3):315-25. doi: 10.1007/BF00499984.
5
Modification of acetylcholine action by bivalent cations on the perfused heart of the frog.二价阳离子对蛙离体心脏乙酰胆碱作用的影响
Recent Adv Stud Cardiac Struct Metab. 1975;7:401-4.
6
[Positive chronotropic and inotropic effects of stimulation of the vagus nerve centers in the frog heart].
Fiziol Zh SSSR Im I M Sechenova. 1985 Mar;71(3):273-8.
7
Motor reactivity of isolated heart of the grass-snake (Natrix natrix L.).
Acta Physiol Pol. 1979 Sep-Dec;30(5-6):607-15.
8
The nicotinic effects of choline esters and of nicotine in guinea pig atria.胆碱酯类和尼古丁对豚鼠心房的烟碱样作用。
J Pharmacol Exp Ther. 1966 Apr;152(1):29-36.
9
Letter: Positive inotropic action of acetylcholine on frog heart.信函：乙酰胆碱对蛙心的正性肌力作用。
Indian J Physiol Pharmacol. 1974 Apr-Jun;18(2):142-3.
10
The mode of action of 4-aminopyridine on the chronotropic and inotropic responses in the isolated, blood-perfused dog heart.4-氨基吡啶对离体血液灌注犬心脏变时性和变力性反应的作用方式。
Eur J Pharmacol. 1985 Aug 27;114(3):317-23. doi: 10.1016/0014-2999(85)90376-0.
Zotero 插件