Durand M, Hoerni B, Lacut J Y, Hoerni-Simon G, Chauvergne J
Ann Med Interne (Paris). 1975 Apr;126(4):251-6.
The main clinical and paraclinical characteristics of 411 infections which occured in 629 patients with malignant lymphoma, treated between 1960 and 1973, are reported here. The theoretical interest of such cases is emphasized, they permit one to contrast Hodgkin's disease with other forms of lymphoma in view of the very marked paraneoplastic immune deficiency in the first group. The practical, diagnostic and therpeutic problems raised are exceptionally difficult and may become even more simple with more efficacious anticancer therapy which, curing more regularly patients from their blood disease, avoids the factors which favour these infections.
本文报告了1960年至1973年间接受治疗的629例恶性淋巴瘤患者中发生的411例感染的主要临床和临床旁特征。强调了此类病例的理论意义,鉴于第一组中非常明显的副肿瘤性免疫缺陷,它们使人们能够将霍奇金病与其他形式的淋巴瘤进行对比。所提出的实际、诊断和治疗问题异常困难,而随着更有效的抗癌治疗,这些问题可能会变得更加简单,因为这种治疗能更常规地治愈患者的血液病,避免那些有利于这些感染的因素。