秋水仙碱对肝素刺激的离体脂肪细胞中清除因子脂肪酶释放的抑制作用。
Colchicine inhibition of the heparin-stimulated release of clearing-factor lipase from isolated fat-cells.
作者信息
Cryer A, McDonald A, Williams E R, Robinson D S
出版信息
Biochem J. 1975 Dec;152(3):717-20. doi: 10.1042/bj1520717.
Abstract
When isolated fat-cells are incubated at 25 degrees C in serum-based media containing glucose, insulin and heparin, the rise that occurs in the clearing-factor lipase activity of the incubation medium is inhibited by colchicine. The rise in the fat-cell clearing-factor lipase activity that occurs during similar incubations in the absence of heparin is not affected by colchicine.
摘要
当分离出的脂肪细胞在含有葡萄糖、胰岛素和肝素的血清培养基中于25摄氏度孵育时，培养基中清除因子脂肪酶活性的升高会被秋水仙碱抑制。在无肝素的类似孵育过程中脂肪细胞清除因子脂肪酶活性的升高不受秋水仙碱影响。
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