Soifer D, Braun T, Hechter O
Science. 1971 Apr 16;172(3980):269-71. doi: 10.1126/science.172.3980.269.
Insulin appears to promote microtubule assemblty in rat adipocytes. Neithler oxytocin nor high concentrations of glucose has this effect. Colchicine inihibits stimulation by insulin of lipid and glycogen synthesis without influencing stimulation by insulin of glucose oxidation. The anabolic effects of oxytocin or high concentrations of glucose are not inhibited by colchicine. The "directive effect" of insulin may involve microtubules.
胰岛素似乎能促进大鼠脂肪细胞中的微管组装。催产素和高浓度葡萄糖都没有这种作用。秋水仙碱抑制胰岛素对脂质和糖原合成的刺激作用，而不影响胰岛素对葡萄糖氧化的刺激作用。秋水仙碱不会抑制催产素或高浓度葡萄糖的合成代谢作用。胰岛素的“定向作用”可能涉及微管。
