Stopford W, Goldwater L J
Environ Health Perspect. 1975 Dec;12:115-8. doi: 10.1289/ehp.7512115.
The danger of methylmercury poisoning appears to be slight when the environment is not directly contaminated with methylmercury. Sediments rapidly bind mercury and decrease its availability to aquatic organisms. Sediments further have a greater propensity to demethylate than to methylate mercury. In noncontaminated aquatic ecosystems, the concentrations of methylmercury and inorganic mercury are many times lower than those that have been found to cause toxicity, even in the most sensitive organisms. Methylmercury bound to protein is comparatively less toxic than methylmercury salts, and selenium present in this protein appear to be one of the major detoxifying agents for methylmercury. This is particularly important in seafood, where there is an excess of selenium compared to methylmercury.
当环境未直接受到甲基汞污染时,甲基汞中毒的风险似乎很小。沉积物会迅速结合汞并降低其对水生生物的可用性。此外,沉积物使汞脱甲基化的倾向大于使其甲基化的倾向。在未受污染的水生生态系统中,甲基汞和无机汞的浓度比已发现会导致毒性的浓度低很多倍,即使在最敏感的生物中也是如此。与蛋白质结合的甲基汞的毒性相对低于甲基汞盐,而该蛋白质中存在的硒似乎是甲基汞的主要解毒剂之一。这在海鲜中尤为重要,因为其中硒的含量相对于甲基汞而言过量。