Krauz V A
Farmakol Toksikol. 1975 Mar-Apr;38(2):138-41.
Aethimizol - and strychnine-induced improvement of the short-term memory in dogs is attened by a rising level of excitability of the mesencephalic reticular formation, ventral hippocampus and of the frontal region of the neocrotex. And, conversely, with the stimulats producing a facilitating effect on the memory the excitability of the dorsal hippocampus, mamillary bodies and the dorso-medial amygdala becomes less intensive. At the same time, the function of the anterio-ventral thalamus, basolateral amygdala and also of the primary visual and accoustic regions of the neocortex remains unchanged. Aethimizol exerts an inhibitory effect on the lateral and ventro-medial hypothalamus whereas strychnine raises the excitability of the later and does not change the function of the ventro-medial hypothalamus. The lack of stimulating effect of caffeine on the memory is due to a different organization of the brain.