Kaverdina N V, Markova G A
Farmakol Toksikol. 1975 Mar-Apr;38(2):173-7.
Data on pharmacology of nonachlazine-a new antianginal preparation effective in the treatment of patients with ischemic heart disease-are presented. The drug tends to greatly improve the blood supply of the heart. Its beneficial action comes from the ability to intensively and protractedly enhance the coronary blood flow, thus increasing the oxygen reserve of the heart with the contractility of the myocardium rising without any substantial changes in the cardiac output and work.
本文介绍了新型抗心绞痛制剂非那嗪的药理学数据,该制剂对缺血性心脏病患者的治疗有效。该药物倾向于显著改善心脏供血。其有益作用源于能够强烈且持久地增加冠状动脉血流量,从而增加心脏的氧储备,同时心肌收缩力增强,而心输出量和心脏做功无实质性变化。