Demchenko I T, Shandor P, Moskalenko Iu E, Kovach A G
Fiziol Zh SSSR Im I M Sechenova. 1975 Aug;61(8):1153-9.
Effect of somatic afferent C fibres stimulation on rCBF (H2 - clearance method) and cerebral tissue pO2 was studied in 20 dogs. MABP and partial pressure of the arterial blood gases were stabilized before and during 3 min stimulation of the sciatic nerves. The blood flow was changed by 32% in the thalamus and by 17% in the hypothalamus during ipsilateral stimulation. Contralateral sciatic nerve stimulation caused smaller but still a significant fall of the rCBF and increase of the CVR in both regions. Parallel to these changes, tissue pO2 decreased by 19% in the hypothalamic and by 25% in the thalamic areas as compared with the prestimulation level.
在20只狗身上研究了躯体传入C纤维刺激对局部脑血流(H2清除法)和脑组织氧分压的影响。在刺激坐骨神经3分钟之前和期间,平均动脉血压(MABP)和动脉血气分压保持稳定。同侧刺激期间,丘脑血流变化了32%,下丘脑血流变化了17%。对侧坐骨神经刺激导致两个区域的局部脑血流(rCBF)下降幅度较小但仍显著,脑血管阻力(CVR)增加。与这些变化同时发生的是,与刺激前水平相比,下丘脑区域的组织氧分压下降了19%,丘脑区域下降了25%。