Beiul E A, Frolova I A, Oleneva V A, Mokina M N
Vopr Pitan. 1975 Jul-Aug(4):40-4.
The glucose-6-phosphate-dehydrogenase activity by the fatty tissue in patients with alimentary adiposity was studied. A well-marked fall of the activity by comparison with controls, especially in patients with hyperlipidemia, was revealed. Following treatment of the patients with reduction diets their falling body weight was paralleled by significantly rising activity of the fatty tissue G-6-P-D. Tests in vitro failed to show pyridozine and pyridoxal-6-phosphate to affect the activity of the enzyme.
对患有营养性肥胖症患者的脂肪组织中的葡萄糖-6-磷酸脱氢酶活性进行了研究。结果显示,与对照组相比,该活性明显下降,尤其是在高脂血症患者中。在对患者采用低热量饮食治疗后,他们体重下降的同时,脂肪组织葡萄糖-6-磷酸脱氢酶的活性显著上升。体外试验未能表明吡哆嗪和磷酸吡哆醛会影响该酶的活性。