Oleneva V A, Beiul E A, Frolova I A, Popova Iu P
Vopr Pitan. 1976 May-Jun(1):38-42.
Data derived from a comparative study of some lipids and water metabolism rates in patients suffering mainly from metabolic-alimentary form of adiposity in 2 age groups (from 16 to 25 and from 35 years and upwards, respectively) are offered. In patients of both groups substantial changes in the lipid fractions of the blood were noted. The proportions of glycerides, beta-lipoproteins and free fatty acids in the blood were markedly increased. At the same time, all the patients, irrespective of their age, demonstrated a fall of the glucose-6-phosphate-dehydrogenase activity of the fatty tissue along with a reduced diurnal excretion of catecholamines with DOPA. There were in evidence characteristic disorders of the water metabolism that found their expression in an increased overall amount of water and also in a higher content of extra- and intracellular fluid. A low-calories diet used in conjunction with graded therapeutic exercises helped achieve a positive dynamics in the reduction of the patients' body weight along with a tendency toward normalization of the study metabolic rates in both of these age groups.
提供了对主要患有代谢 - 营养型肥胖的两个年龄组（分别为16至25岁以及35岁及以上）患者的一些脂质和水代谢率进行比较研究得出的数据。在两组患者中均发现血液脂质成分有显著变化。血液中甘油酯、β - 脂蛋白和游离脂肪酸的比例明显增加。与此同时，所有患者，无论年龄大小，脂肪组织中葡萄糖 - 6 - 磷酸脱氢酶活性均下降，且儿茶酚胺与多巴的日间排泄量减少。有证据表明存在水代谢的特征性紊乱，表现为总体水量增加以及细胞外液和细胞内液含量升高。结合分级治疗性运动使用的低热量饮食有助于在降低患者体重方面取得积极进展，同时这两个年龄组的研究代谢率有趋于正常化的趋势。
