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A special photoproduct of UV-irradiated DNA in vacuo.

作者信息

Bucker H, Dose K, Horneck G, Thomas C

机构信息

DFVLR, Institut fur Flugmedizin, Frankfurt/M. FRG.

出版信息

Life Sci Space Res. 1979;17:111-5. doi: 10.1016/b978-0-08-023416-8.50018-0.

Abstract

DNA isolated from E. coli B/r cells was UV-irradiated at 254 nm under high vacuum of 10(-7) torr. Compared with DNA in solution, the formation of cis-syn thymine dimers (TT) was decreased, and the formation of cytosine thymine dimers (CT) and a photoproduct of RF value 0.41 was increased. The latter photoproduct was identified as tran-syn TT which is preferentially produced in heat-denaturated DNA.

摘要

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