Granja Cristina, Cabral Glória, Pinto Armando Teixeira, Costa-Pereira Altamiro
Intensive Care Unit, Resuscitation Committee, Hospital Pedro Hispano, 4450 Matosinhos, Portugal.
Resuscitation. 2002 Oct;55(1):37-44. doi: 10.1016/s0300-9572(02)00203-4.
Evaluation of outcome after cardiac arrest focuses mainly on survival. Survivors of cardiac arrest end up in different states of health and survival alone may not be a sensitive measure for successful cardiopulmonary resuscitation (CPR).
To evaluate health-related quality of life (HR-QOL) of cardiac arrest survivors with EQ-5D, a generic instrument developed by the EuroQol group.
From April 1997 to December 2000, all cardiac arrest adult patients admitted to an eight-bed medical/surgical (ICU) of a tertiary care hospital were enrolled. At 6-months after ICU discharge survivors attended a follow-up interview and answered EQ-5D questionnaire. A match-control group was created choosing for each survivor of cardiac arrest two controls, with similar age range (+/-5 years) and similar Apache II (+/-3 Apache II units), that were randomly selected among other ICU patients.
From a total of 1106 patients, 97 (9%) patients were admitted after cardiac arrest. Forty-seven patients (48%) were discharged from ICU. Of these, 11 patients died in the ward. Thirty-six (37%) patients were discharged from hospital. Twelve patients died after hospital discharge but before 6-month evaluation. Five patients were not evaluated, three because they were living in distant locations and two for unknown reasons. Nineteen patients attended the follow-up consultation. Eight of these patients were actively working and six of them had managed to return to their previous activity. Eleven patients were retired and seven of these managed to return to their previous level of activity while four patients presented with anoxic encephalopathy: one with mild and one with moderate neurological dysfunction, two with severe anoxic neurological dysfunction. Although a higher percentage of cardiac arrest survivors reported more extreme problems in some dimensions than other ICU patients, no significant differences were found on HR-QOL, when evaluated by EQ-5D.
When evaluated with EQ-5D at 6-months after ICU discharge, survivors of cardiac arrest exhibit a HR-QOL similar to other ICU survivors. These results agree with previous reports stating that CPR is frequently unsuccessful but if survival is achieved a fairly good quality of life can be expected.
心脏骤停后结局评估主要关注生存情况。心脏骤停幸存者最终处于不同的健康状态,仅生存下来可能并非成功心肺复苏(CPR)的敏感指标。
使用欧洲生活质量研究组开发的通用工具EQ-5D评估心脏骤停幸存者的健康相关生活质量(HR-QOL)。
1997年4月至2000年12月,纳入一家三级医院拥有8张床位的内科/外科重症监护病房(ICU)收治的所有成年心脏骤停患者。ICU出院6个月后,幸存者接受随访访谈并回答EQ-5D问卷。为每位心脏骤停幸存者选择两名年龄范围相似(±5岁)且急性生理与慢性健康状况评分系统II(APACHE II)相似(±3个APACHE II单位)的对照,在其他ICU患者中随机选取组成匹配对照组。
在总共1106例患者中,97例(9%)患者心脏骤停后入院。47例患者(48%)从ICU出院。其中,11例患者在病房死亡。36例(37%)患者出院。12例患者出院后但在6个月评估前死亡。5例患者未接受评估,3例因居住在偏远地区,2例原因不明。19例患者参加了随访咨询。这些患者中8例仍在积极工作,其中6例已设法恢复到之前的活动状态。11例患者已退休,其中7例设法恢复到之前的活动水平,4例患者出现缺氧性脑病:1例轻度和1例中度神经功能障碍,2例重度缺氧性神经功能障碍。尽管与其他ICU患者相比,更高比例的心脏骤停幸存者在某些维度报告了更极端的问题,但通过EQ-5D评估时,在HR-QOL方面未发现显著差异。
ICU出院6个月后使用EQ-5D评估时,心脏骤停幸存者的HR-QOL与其他ICU幸存者相似。这些结果与先前报告一致,即CPR常常不成功,但如果存活下来,可以预期有相当好的生活质量。