Bardzik J, Przeździak J, Bardzik I
Anaesth Resusc Intensive Ther. 1975 Oct-Dec;3(4):285-90.
In 18 persons (anaesthetists and anaesthetic nurses) with a history of long-term exposure to low concentrations of halothane the activity of aminotransferases, GGTP, and alkaline phosphatase, the bilirubin level and thymol turbidity test were determined and no significant abnormalities were found. On the other hand, determinations of immunoglobulons showed changes in the raised IgM level in 15 out of 18 persons, the difference between the normal level and that found in the present studies being statistically significant. The levels of IgA and IgG were within the normal range. Raised IgM level may be due to stimulation of the immune system by halothane.
对18名有长期接触低浓度氟烷病史的人员（麻醉师和麻醉护士）进行了检测，测定了其转氨酶、γ-谷氨酰转肽酶（GGTP）和碱性磷酸酶的活性、胆红素水平以及麝香草酚浊度试验，未发现明显异常。另一方面，免疫球蛋白检测显示，18人中有15人的IgM水平升高，正常水平与本研究中所测水平之间的差异具有统计学意义。IgA和IgG水平在正常范围内。IgM水平升高可能是氟烷刺激免疫系统所致。
