Grosshans E, Vetter J M, Capesius M C
Ann Anat Pathol (Paris). 1975 Aug-Oct;20(4):381-94.
Malignant eccrine poromas set first of all the problem of the diagnosis of intra-epidermic cutaneous tumours. The epidermic symbiosis of the neoplastic cells and their natural disposition to keratinization and to differentiation of excretosudoral structures are their main pathological characteristics; they account for their acrosyringeal origin. The multitude of epidermotropic metastatic resurgences by the lymphatic route and their transcutaneous expulsion characterizes the evolution of these tumours. According to the study of the 8 cases published since 1956 and of this personal case the precession of a benign porosyringeal tumour seems probable but has never been proved.
恶性小汗腺汗孔瘤首先带来了表皮内皮肤肿瘤的诊断问题。肿瘤细胞的表皮共生及其向角质形成和排泄汗腺结构分化的自然倾向是其主要病理特征；这解释了它们的顶泌汗腺起源。这些肿瘤的发展特征为通过淋巴途径出现大量亲表皮转移性复发以及经皮排出。根据对1956年以来发表的8例病例以及本病例的研究，良性小汗腺汗孔瘤的前驱病变似乎有可能，但从未得到证实。
