Balabaud C, Roche M C, Dangoumau J
Biomedicine. 1975 Nov 10;23(9):353-5.
Hepatic blood flow was measured in the unanesthetized rabbit using the clearance technique of 198Au and 125I RB. The values are: 71.82 +/- 16.24 ml-min-1-kg-1 for 198Au, and 60.21+/-9.94 ml-min-1-kg-1 for 125I RB (P less than 0.01). The overestimation of HBF with colloidal gold is probably due to extra splanchnic sequestration which has been estimated to be 15+/-3%. The week extraction of RB limits the use of this dye for measurements of HBF. HBF is easier to measure with 198 Au.
采用¹⁹⁸Au和¹²⁵I标记的人血清白蛋白(¹²⁵I RB)清除技术,在未麻醉的兔身上测量肝血流量。结果如下:¹⁹⁸Au测得的值为71.82±16.24毫升·分钟⁻¹·千克⁻¹,¹²⁵I RB测得的值为60.21±9.94毫升·分钟⁻¹·千克⁻¹(P<0.01)。用胶体金高估肝血流量可能是由于内脏外潴留,据估计其为15±3%。¹²⁵I RB摄取率低限制了该染料用于肝血流量测量。用¹⁹⁸Au测量肝血流量更容易。