De Vita C, De Ponti C, Pioselli D, Bossi M
G Ital Cardiol. 1975;5(4):513-25.
Intraventricular conduction disturbances (IVD) were found in 181 (21,9%) out of 828 patients with acute myocardial infarction. Isolated RBBB was present in 6,3% of cases; both RBBB and LAH or LPH in 3,4%; isolated LAH in 5,8%; LBBB in 3%; suspect blocks of the three brances [RBBB+LAH+first degree atrio-ventricular block (AVB), or LBBB+first degree AVB] in 2,9% of cases. The severe mortality (41%) during hospitalisation of patients with IVB seems to be due to the haemodynamic impairement: cardiogrnic shock was observed in 20% of these patiens and acute pulmonary oedema in 18%. Transient or permanent complete AVB occurred during hospitalisation in 24,3% of these patients. The occurrence of complete AVB was higher (54%) in patients in whom suspect block of three branches was present. It was found that the progression of IVD to complete AVB increased the mortality rate to 48%. The short term prognosis of patients with IVD does not seem to be improved by prophilactic electrical stimulation, but the rate of deaths for asystolia is reduced. The mortality rate after one year of patients discharged from hospital was 25%; suspect three branches IVD died suddenly and 2 progressed to complete AVB. In the author's opinion the implantation of permanent electrical stimulation is indicated in patients showing IVD of the three branches assessed using His bundle electrgram during the acute phase of myocardial infarction.
在828例急性心肌梗死患者中,发现181例(21.9%)存在室内传导障碍(IVD)。孤立性右束支传导阻滞(RBBB)占6.3%;RBBB合并左前分支阻滞(LAH)或左后分支阻滞(LPH)占3.4%;孤立性LAH占5.8%;左束支传导阻滞(LBBB)占3%;疑似三支阻滞[RBBB + LAH + 一度房室传导阻滞(AVB),或LBBB + 一度AVB]占2.9%。IVB患者住院期间的严重死亡率(41%)似乎是由于血流动力学受损:这些患者中20%出现心源性休克,18%出现急性肺水肿。24.3%的患者在住院期间发生短暂或永久性完全性AVB。在存在疑似三支阻滞的患者中,完全性AVB的发生率更高(54%)。发现IVD进展为完全性AVB会使死亡率增至48%。预防性电刺激似乎并未改善IVD患者的短期预后,但可降低心脏停搏的死亡率。出院一年后患者的死亡率为25%;疑似三支IVD患者突然死亡,2例进展为完全性AVB。作者认为,对于在心肌梗死急性期使用希氏束电图评估显示三支IVD的患者,应植入永久性电刺激装置。