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振动对眼部硫酸黏多糖代谢的影响。

Effect of vibration on sulfomucopolysaccharide metabolism in the eye.

作者信息

Dabrowska J

出版信息

Invest Ophthalmol. 1975 Mar;14(3):250-2.

PMID:123232
Abstract

The metabolism of 35S sodium sulfate was studied in the eyes of guinea pigs and rabbits subjected to vibration. The investigations included determination of radioactivity of whole eyeballs of guinea pigs and in single eyeball tunics of rabbits, i.e., retina-choroid-sclera investigated jointly as a tissue complex, and cornea and lens studied separately, besides that, autoradiographic investigations were performed. The animals were subjected to a vertical, sinusoidal vibration of 42 Hz. frequency and 1 mm. amplitude. The duration of one exposure was three hours and they were repeated daily for three to six days. Incorporation of the isotope into the eyeballs of animals subjected to vibration was decreased and this decrease was related to the length of exposure suggesting that vibration changes the metabolism of sulfomucopolysaccharides in the eye.

摘要

对遭受振动的豚鼠和兔子的眼睛进行了35S硫酸钠的代谢研究。研究包括测定豚鼠全眼球以及兔子单个眼球组织层的放射性,即视网膜 - 脉络膜 - 巩膜作为一个组织复合体联合研究,角膜和晶状体分别研究,此外还进行了放射自显影研究。动物接受频率为42Hz、振幅为1mm的垂直正弦振动。一次暴露持续时间为3小时,每天重复,持续3至6天。遭受振动的动物眼球中同位素的掺入减少,且这种减少与暴露时间长短有关,这表明振动改变了眼睛中硫黏多糖的代谢。

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