Kohno T, Sorgente N, Patterson R, Ryan S J
Jpn J Ophthalmol. 1983;27(3):496-505.
Using immunofluorescent techniques we have examined the distribution of the glycoproteins, fibronectin and laminin, in bovine eyes. As expected, both fibronectin and laminin were present in blood vessel walls and in all basement membranes, including the internal limiting membrane of the retina. Fibronectin, but not laminin, was observed arranged in fine fibrillar arrays within the vitreous body. The presence of fibronectin in the vitreous cortex and the occurrence of both proteins in the internal limiting membrane of the retina provide a morphologic suggestion of a role for fibronectin and laminin in vitreoretinal adhesion.
我们运用免疫荧光技术检测了糖蛋白、纤连蛋白和层粘连蛋白在牛眼内的分布情况。正如预期的那样，纤连蛋白和层粘连蛋白均存在于血管壁以及包括视网膜内界膜在内的所有基底膜中。在玻璃体中观察到纤连蛋白呈细纤维状排列，而层粘连蛋白则未观察到这种情况。玻璃体皮质中存在纤连蛋白以及视网膜内界膜中同时存在这两种蛋白，从形态学角度提示了纤连蛋白和层粘连蛋白在玻璃体视网膜粘连中发挥作用。
