Seige K, Ulrich E
Z Gesamte Inn Med. 1975 May;30(9):37-42.
The therapy of diabetes mellitus is always connected with the observation of an adapted diet, the aim of which is the obtaining of the optimal weight. Still more intensive concentric educational measures for patients and persons endangered by diabetes are necessary, in which cases muscular action is of increasing importance. Sulfonylureas furthering the secretion of insulin are to be used only as far as necessary. Peripherally acting anti-diabetics, such as biguanides have an indication in diabetes mellitus which is exactly defined and to be observed. Also with regard to the combat against adiposity their influence on the lipometabolism needs further clarification. Metabolic and immunologic insulin resistance are complications of the insulin therapy. The extensive technical preparation of the human synthetic insulin may contribute to the improvement of the prognosis of diabetes. At present the introduction of artifical beta-cell-systems is a problem of the diminishing of the apparatuses. The genetic consultation for diabetics is important and in many cases possible.
糖尿病的治疗始终与遵循适应性饮食的观察相关联，其目的是达到最佳体重。对于糖尿病患者和有糖尿病风险的人，还需要更深入、更集中的教育措施，在这些情况下，肌肉活动的重要性日益凸显。促进胰岛素分泌的磺脲类药物仅在必要时使用。外周作用的抗糖尿病药物，如双胍类药物，在糖尿病中有明确规定且需遵循的适应症。在对抗肥胖方面，它们对脂肪代谢的影响仍需进一步阐明。代谢性和免疫性胰岛素抵抗是胰岛素治疗的并发症。人工合成胰岛素的广泛技术制备可能有助于改善糖尿病的预后。目前，引入人工β细胞系统是设备小型化的一个问题。糖尿病患者的遗传咨询很重要，而且在很多情况下是可行的。
