芳基三氮烯体外氧化N-去甲基化的研究 - Suppr

Suppr

超能文献

Investigation on the oxidative N-demethylation of aryl triazenes in vitro.

作者信息

Giraldi T, Nisi C, Sava G

出版信息

Biochem Pharmacol. 1975 Oct 1;24(19):1793-7. doi: 10.1016/0006-2952(75)90459-1.

DOI:10.1016/0006-2952(75)90459-1

PMID:1233982

Abstract

摘要

相似文献

Investigation on the oxidative N-demethylation of aryl triazenes in vitro.芳基三氮烯体外氧化N-去甲基化的研究

Biochem Pharmacol. 1975 Oct 1;24(19):1793-7. doi: 10.1016/0006-2952(75)90459-1.

Observations on the "in vitro" oxidative N-demethylation of 4-(3, 3-dimethyl-1-triazeno)-imidazole-5-carboxamide (DIC, NSC 45388).关于4-（3,3-二甲基-1-三氮烯基）-咪唑-5-甲酰胺（DIC，NSC 45388）的“体外”氧化N-去甲基化的观察

Pharmacol Res Commun. 1976 Feb;8(1):25-9. doi: 10.1016/0031-6989(76)90026-6.

Microsomal mediated metabolism of dialkylaryltriazenes. I. Demethylation of ring halogenated 3,3-dimethyl-1-phenyltriazenes.微粒体介导的二烷基芳基三氮烯的代谢。I. 环卤代3,3-二甲基-1-苯基三氮烯的去甲基化作用

J Cancer Res Clin Oncol. 1979 Apr 12;93(3):215-20. doi: 10.1007/BF00964576.

Triazene metabolism. I. The effect of substituents in the aryl group on the kinetics of enzyme-catalysed N-demethylation of 1-aryl-3,3-dimethyltriazenes.三氮烯代谢。I. 芳基上取代基对1-芳基-3,3-二甲基三氮烯酶催化N-去甲基化动力学的影响。

Can J Physiol Pharmacol. 1981 Dec;59(12):1234-8. doi: 10.1139/y81-193.

Microsomal mediated metabolism of dialkylaryltriazenes. II. Isolation and identification of metabolites of 3,3-dimethyl-1-phenyltriazene.微粒体介导的二烷基芳基三氮烯的代谢。II. 3,3-二甲基-1-苯基三氮烯代谢产物的分离与鉴定。

J Cancer Res Clin Oncol. 1979 Apr 12;93(3):221-31. doi: 10.1007/BF00964577.

Oxidative demethylation of 14C-griseofulvin by liver microsomes of rats and mice.大鼠和小鼠肝脏微粒体对14C-灰黄霉素的氧化脱甲基作用。

Biochem Pharmacol. 1973 Jun 1;22(11):1389-92. doi: 10.1016/0006-2952(73)90314-6.

Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine.

Chem Pharm Bull (Tokyo). 1976 Dec;24(12):3229-31. doi: 10.1248/cpb.24.3229.

The formation and metabolism of N-hydroxymethyl compounds--I. The oxidative N-demethylation of N-dimethyl derivatives of arylamines, aryltriazenes, arylformamidines and arylureas including the herbicide monuron.N-羟甲基化合物的形成与代谢——I. 芳胺、芳基三氮烯、芳基甲脒和芳基脲的N-二甲基衍生物的氧化N-脱甲基作用，包括除草剂灭草隆。

Biochem Pharmacol. 1982 Nov 15;31(22):3621-7. doi: 10.1016/0006-2952(82)90585-8.

Antitumour activity, biomimetic oxidation and metabolism of heteroalicyclic triazenes.杂环脂环族三氮烯的抗肿瘤活性、仿生氧化与代谢

Biochem Pharmacol. 1979 Mar 15;28(6):769-76. doi: 10.1016/0006-2952(79)90357-5.

Oxidative metabolism of 1-(2-chloroethyl)-3-alkyl-3- (methylcarbamoyl)triazenes: formation of chloroacetaldehyde and relevance to biological activity.1-（2-氯乙基）-3-烷基-3-（甲基氨基甲酰基）三氮烯的氧化代谢：氯乙醛的形成及其与生物活性的关系

Chem Res Toxicol. 1996 Jan-Feb;9(1):172-8. doi: 10.1021/tx9500639.

引用本文的文献

Effects of an inducer and an inhibitor of hepatic metabolism on the antitumor action of dimethyltriazenes.肝脏代谢诱导剂和抑制剂对二甲基三氮烯抗肿瘤作用的影响。

Cancer Chemother Pharmacol. 1988;21(3):241-5. doi: 10.1007/BF00262778.

Antineoplastic action of p-(3-methyl-1-triazeno)benzoic acid potassium salt, a monomethyl derivative of the antimetastatic compound DM-COOK.对-（3-甲基-1-三氮烯基）苯甲酸钾盐的抗肿瘤作用，抗转移化合物DM-COOK的单甲基衍生物

Cancer Chemother Pharmacol. 1991;27(6):423-8. doi: 10.1007/BF00685155.

Some aspects of metabolic activation of chemical carcinogens in relation to their organ specificity.化学致癌物代谢活化与其器官特异性相关的一些方面。

Arch Toxicol. 1977 Dec 30;39(1-2):51-63. doi: 10.1007/BF00343275.

J Cancer Res Clin Oncol. 1979 Apr 12;93(3):221-31. doi: 10.1007/BF00964577.

J Cancer Res Clin Oncol. 1979 Apr 12;93(3):215-20. doi: 10.1007/BF00964576.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验