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硬膜外血肿。对100例患者的回顾性研究。

Epidural haematoma. A retrospective study of 100 patients.

作者信息

Jonker C, Oosterhuis H J

出版信息

Clin Neurol Neurosurg. 1975;78(4):233-45. doi: 10.1016/0303-8467(75)90002-5.

Abstract

A retrospective study was made of 100 consecutive patients with an epidural haematoma in order to establish which clinically demonstrable factors had influenced the prognosis quoad vitam et sanationem. Operations were performed on 92 of these patients, 29 (32%) of whom died; 8 patients died without operation, and in 2 of these cases the diagnosis was not made during life. A lucid interval was observed in 57 patients; absence of a lucid interval in combination with a lowered sensory level indicated associated intradural lesions (cerebral contusion, acute subdural haematoma), with consequently a less good prognosis. The prognosis was also adversely affected by deeper coma, occurrence of extensor spasms, bilateral stiff pupils, bilateral pyramidal symptoms and an age over 50. Some 33% of the patients treated by operation showed marked symptoms of compression (extensor spasms and/or bilateral stiff pupils); although these symptoms are usually described as indicative of a hopeless prognosis, 40% of the patients in this catagory survived. Contrary to the data in the literature, the interval between accident and operation within the first 24 hours did not influence the mortality, which was 50%. All patients operated on more than 24 hours after the accident, survived. A cranial fracture was absent in 13 patients, 11 of whom were under 30; absence of a cranial fracture was prognostically favourable. A catamnestic study revealed that 7 of the 58 accessible survivors had residual neurological dysfunctions; all these patients were up and about. The residual morbidity after early operation (within 24 hours) was the same as that after later operation. The data obtained were compared with those on a number of series recently published in the literature.

摘要

对100例连续性硬膜外血肿患者进行了回顾性研究,以确定哪些临床可证实的因素影响了生死及康复的预后。其中92例患者接受了手术,29例(32%)死亡;8例患者未手术死亡,其中2例生前未确诊。57例患者出现了清醒期;清醒期缺失并伴有感觉水平降低提示存在硬膜内相关病变(脑挫伤、急性硬膜下血肿),因此预后较差。较深的昏迷、伸肌痉挛的出现、双侧瞳孔僵硬、双侧锥体束征以及年龄超过50岁也对预后产生不利影响。约33%接受手术治疗的患者出现明显的压迫症状(伸肌痉挛和/或双侧瞳孔僵硬);尽管这些症状通常被描述为预后无望的指标,但该类别中40%的患者存活下来。与文献数据相反,事故后24小时内手术间隔时间并未影响死亡率,死亡率为50%。事故后24小时以上接受手术的所有患者均存活。13例患者无颅骨骨折,其中11例年龄在30岁以下;无颅骨骨折在预后方面较为有利。随访研究显示,58例可随访的幸存者中有7例存在残留神经功能障碍;所有这些患者均可自由活动。早期手术(24小时内)后的残留发病率与晚期手术相同。将获得的数据与文献中最近发表的一系列数据进行了比较。

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