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[The antibacterial action of the amoxicillin-flucloxacillin combination].

作者信息

Carlone N A, Savoia D, Martinetto P

出版信息

G Batteriol Virol Immunol. 1975 Jul-Dec;68(7-12):289-300.

PMID:1234595
Abstract

A mixture of amoxycillin, semisynthetic penicillin beta-lactamase susceptible, and flucloxacillin, an isoxazolylpenicillin, in combination 1:1 was tested. This mixture shows real synergic effect "in vitro" on beta-lactamase producing Gram-positive and Gramnegative bacteria and an additive effect on the other microrganisms. Good results have been obtained "in vivo" and a protective effect of flucloxacillin on enzymatic degradation of amoxycillin by beta-lactamase was found.

摘要

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