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[Metabolic activity of the N-acetylneuraminic acid of the principle gangliosides of the brain].

作者信息

Prokhorova M I, Bespalova M A, Mukhina A P, Tumanova S Iu

出版信息

Vopr Biokhim Mozga. 1975;10:182-6.

PMID:1234668
Abstract

The turnover rate of N-acetylneuraminic acid of brain gangliosides (GT1, GD1b, GD1a, GM1) was studied following the injection of 2-14C-acetate. The specific activity of N-acetylneuraminic acid in GD1a and GM1 was found to be higher than in GD1b. The administration of aminasine reduced the specific activity of N-acetylneuraminic acid whereas chlorhydrate increased that of major brain ganglosides.

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