Wu Jingcun, Mullett W M, Pawliszyn Janusz
Anal Chem. 2002 Sep 15;74(18):4855-9. doi: 10.1021/ac025595q.
Solid-phase microextraction (SPME) fiber coatings based on conductive polypyrrole films were prepared for the electrochemical extraction and desorption of ionic analytes. Simple preparation of each of the PPY extraction coatings on a platinum wire was possible with a constant potential method, but more importantly, cycling of the film between oxidation and reduction potentials facilitated the extraction and desorption of ionic analytes. The analytes were desorbed into a sample aliquot of water and were determined by flow injection analysis using a mass spectrometer. The fiber coatings and the developed electrochemical SPME method were found to be stable and reproducible (RSD < 5%; N = 5) and could be extended to several cations and anions, confirming the versatility of the approach. Preconcentration of the analyte on the fiber was also possible by repeating the processes to increase the amount of analyte extracted.
制备了基于导电聚吡咯膜的固相微萃取（SPME）纤维涂层，用于离子分析物的电化学萃取和解吸。采用恒电位法可在铂丝上简单地制备每种聚吡咯萃取涂层，但更重要的是，膜在氧化电位和还原电位之间循环促进了离子分析物的萃取和解吸。分析物解吸到一份水样中，然后用质谱仪通过流动注射分析进行测定。结果发现，纤维涂层和所开发的电化学SPME方法稳定且可重复（相对标准偏差<5%；N = 5），并且可以扩展到多种阳离子和阴离子，证实了该方法的通用性。通过重复这些过程以增加萃取的分析物量，也可以在纤维上对分析物进行预富集。
