Stark E, Acs Z, Palkovits M, Folly G
Acta Physiol Acad Sci Hung. 1975;46(2):115-24.
Corticosteroid receptors were demonstrated in the medial hypothalamus, the hippocampus and the parietal cortex of the rat while no such receptors were found in the hypophysis, the amygdala and the anterior hypothalamus. The findings suggest the role of extrahypothalamic regions in the perception of corticosteroid feedback as well as in the regulation of the hypothalamo-hypophysial-adrenal function and do not support the assumption that corticosteroids would inhibit corticotrophin secretion by acting directly on the hypophysis.
在大鼠的内侧下丘脑、海马体和顶叶皮质中发现了皮质类固醇受体，而在垂体、杏仁核和下丘脑前部未发现此类受体。这些发现表明下丘脑外区域在皮质类固醇反馈感知以及下丘脑 - 垂体 - 肾上腺功能调节中发挥作用，并不支持皮质类固醇会通过直接作用于垂体来抑制促肾上腺皮质激素分泌这一假设。
