Hensle Terry W, Kearney Michael C, Bingham Jonathan B
Division of Pediatric Urology, Childrens Hospital of New York, New York, NY, USA.
J Urol. 2002 Oct;168(4 Pt 2):1734-6; discussion 1736-7. doi: 10.1097/01.ju.0000027178.94140.00.
We review the long-term results of buccal mucosa grafts used as part of secondary hypospadias repair.
We evaluated 47 patients for 10 years and analyzed long-term results of buccal mucosa grafts for hypospadias repair. Of the 47 patients 40 have been followed for more than 3 years.
The overall complication rate was 32% (13 of 47 cases). All complications occurred in the first 6 months following surgery, and the complication rate was significantly lower in the last 7 years of the series (19%) compared to the first 3 years (60%) (p = 0.01). All 3 patients in this series with a preoperative diagnosis of balanitis xerotica obliterans had a significant postoperative complication.
Buccal mucosa appears to be a durable source of nongenital tissue for urethral replacement. Attention to detail in terms of graft harvest, graft preparation and graft fixation helps to avoid major postoperative complications. Onlay grafts appear to be preferable to tube grafts, and patients with the diagnosis of balanitis xerotica obliterans would appear not to be candidates for 1-stage urethral reconstruction using buccal mucosa.
我们回顾了作为二期尿道下裂修复一部分使用颊黏膜移植物的长期结果。
我们对47例患者进行了10年的评估,并分析了颊黏膜移植物用于尿道下裂修复的长期结果。47例患者中,40例随访时间超过3年。
总体并发症发生率为32%(47例中的13例)。所有并发症均发生在术后前6个月,该系列最后7年的并发症发生率(19%)显著低于前3年(60%)(p = 0.01)。该系列中术前诊断为闭塞性干燥性龟头炎的所有3例患者术后均出现明显并发症。
颊黏膜似乎是用于尿道替代的非生殖组织的持久来源。在移植物获取、移植物制备和移植物固定方面注重细节有助于避免重大术后并发症。覆盖式移植物似乎比管状移植物更可取,而诊断为闭塞性干燥性龟头炎的患者似乎不适合使用颊黏膜进行一期尿道重建。