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一期经口黏膜背侧镶嵌尿道成形术治疗前尿道狭窄。

One-stage dorsal inlay oral mucosa graft urethroplasty for anterior urethral stricture.

机构信息

Department Of Urology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.

出版信息

BMC Urol. 2014 May 8;14:35. doi: 10.1186/1471-2490-14-35.

Abstract

BACKGROUND

Anterior urethral stricture remains a great challenge. We reported our clinical technique and results by using inlay dorsal buccal mucosal graft urethroplasty for repair of anterior urethral stricture.

METHODS

From January 2005 to July 2008, 87 male patients (range from 9 to 72 years old) with anterior urethral stricture have been treated by one-stage dorsal inlay oral mucosal graft (OMG) urethroplasty. All patients gave written informed consent for their participation. All patients showed that urethral plate had been either scarred or removed previously. In our surgery, the urethra was dissected dorsally and scar of the urethral plate was removed. The remnant urethral plate was split at midline and a buccal mucosa patch was inserted between the two parts. Neourethra was tubularized and covered with dartos flap. The pre-operative assessments included clinical data, urine analysis, uroflowmetry, retrograde and voiding cystogram, urethral ultrasonography and endoscopy. Postoperatively, the flow rate and void residual volume were analyzed by uroflowmetry and sonography. Any further instrumentation to assist voiding was considered as failure.

RESULTS

After 12 to 48 months (mean: 25.8 months), 78 patients (89.66%) have shown good results by the one-stage urethroplasty. However, 9 patients (10.3%) required further treatment due to recurrence, while 6 patients (6.9%) had fistula.

CONCLUSIONS

This one-stage dorsal inlay approach using dorsal oral mucosal grafts is a reliable method to create a substitute urethral plate for tubularization. This approach represents a safe option for anterior urethral stricture patients especially with grossly scarred urethral plate.

摘要

背景

前尿道狭窄仍然是一个巨大的挑战。我们报告了我们的临床技术和结果,即使用嵌入式背侧颊黏膜移植物尿道成形术修复前尿道狭窄。

方法

2005 年 1 月至 2008 年 7 月,87 例男性前尿道狭窄患者(年龄 9-72 岁)接受了一期背侧嵌入式口腔黏膜移植物(OMG)尿道成形术治疗。所有患者均书面同意参与。所有患者的尿道板均有瘢痕或先前切除。在我们的手术中,尿道在背侧被解剖,尿道板的瘢痕被切除。残余的尿道板在中线处分裂,将颊黏膜片插入两部分之间。新尿道被管状化,并覆盖以筋膜瓣。术前评估包括临床数据、尿液分析、尿流率测定、逆行和排空膀胱造影、尿道超声和内镜检查。术后,通过尿流率测定和超声分析流速和排空残余量。任何进一步协助排尿的器械都被认为是失败的。

结果

一期尿道成形术后 12-48 个月(平均 25.8 个月),78 例患者(89.66%)获得良好结果。然而,9 例患者(10.3%)因复发需要进一步治疗,6 例患者(6.9%)出现瘘管。

结论

这种使用背侧口腔黏膜移植物的一期嵌入式方法是一种可靠的方法,可以为管状化创造替代尿道板。对于前尿道狭窄患者,尤其是尿道板严重瘢痕的患者,这种方法是一种安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6592/4030733/668a212ccc85/1471-2490-14-35-1.jpg

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