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肝细胞癌筛查

Screening for hepatocellular carcinoma.

作者信息

Koteish Ayman, Thuluvath Paul J

机构信息

Department of Medicine, Johns Hopkins University School of Medicine, 1830 Monument Street, Room 429, Building 1830, Baltimore, MD 21025, USA.

出版信息

J Vasc Interv Radiol. 2002 Sep;13(9 Pt 2):S185-90. doi: 10.1016/s1051-0443(07)61785-0.

DOI:10.1016/s1051-0443(07)61785-0
PMID:12354835
Abstract

To determine the role of screening and to screen in a cost-effective manner, it is important to define the high-risk patient population that is most likely to benefit from screening and to identify a readily available diagnostic modality that is sensitive, specific, and inexpensive. Moreover, to have a major effect on the outcome of hepatocellular carcinoma, the test should be applicable in the majority of high-risk subjects. Herein, we identify the high-risk patient population, discuss various diagnostic modalities, and recommend a practical and cost-effective strategy for screening.

摘要

为了确定筛查的作用并以具有成本效益的方式进行筛查,重要的是定义最有可能从筛查中受益的高危患者群体,并确定一种易于获得、敏感、特异且廉价的诊断方法。此外,为了对肝细胞癌的治疗结果产生重大影响,该检测应适用于大多数高危受试者。在此,我们确定高危患者群体,讨论各种诊断方法,并推荐一种实用且具有成本效益的筛查策略。

相似文献

1
Screening for hepatocellular carcinoma.肝细胞癌筛查
J Vasc Interv Radiol. 2002 Sep;13(9 Pt 2):S185-90. doi: 10.1016/s1051-0443(07)61785-0.
2
Imaging evaluation of hepatocellular carcinoma.肝细胞癌的影像学评估
J Vasc Interv Radiol. 2002 Sep;13(9 Pt 2):S173-84. doi: 10.1016/s1051-0443(07)61784-9.
3
Screening for hepatocellular carcinoma in cirrhosis.肝硬化患者肝细胞癌的筛查
J Hepatol. 2003 Dec;39(6):1076-84. doi: 10.1016/s0168-8278(03)00349-0.
4
[Mass screening for high risk group of hepatocellular carcinoma].[肝细胞癌高危人群的大规模筛查]
Nihon Rinsho. 2001 Oct;59 Suppl 6:786-90.
5
Screening for hepatocellular carcinoma in patients with cirrhosis in the United States: results of a national survey.美国肝硬化患者肝细胞癌筛查:一项全国性调查结果
Am J Gastroenterol. 1999 Aug;94(8):2224-9. doi: 10.1111/j.1572-0241.1999.01297.x.
6
Thrombocytopenia as a surrogate for cirrhosis and a marker for the identification of patients at high-risk for hepatocellular carcinoma.血小板减少作为肝硬化的替代指标及肝细胞癌高危患者的识别标志物。
Cancer. 2006 Nov 1;107(9):2212-22. doi: 10.1002/cncr.22242.
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Detection of hepatocellular cancer during screening of 1125 patients with chronic hepatitis virus infection.在对1125例慢性肝炎病毒感染患者进行筛查期间检测肝细胞癌。
J Chemother. 1997 Apr;9(2):151-2. doi: 10.1179/joc.1997.9.2.151.
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Liver cancer: on the rise.
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Incidence and risk factors of hepatocellular carcinoma in patients with primary biliary cirrhosis.原发性胆汁性肝硬化患者肝细胞癌的发病率及危险因素
Hepatology. 2010 Dec;52(6):2239; author reply 2239-40. doi: 10.1002/hep.24005.
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Screening for hepatocellular carcinoma in high-risk patients: Western versus Eastern virus.高危患者肝细胞癌的筛查:西方病毒与东方病毒
Hepatology. 2003 Jul;38(1):269; author reply 270. doi: 10.1053/jhep.2003.50236.

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PLoS One. 2017 Jan 18;12(1):e0166188. doi: 10.1371/journal.pone.0166188. eCollection 2017.
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World J Hepatol. 2016 Jul 28;8(21):881-90. doi: 10.4254/wjh.v8.i21.881.
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Int J Clin Exp Pathol. 2015 Oct 1;8(10):13725-38. eCollection 2015.
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Intention to treat outcome of T1 hepatocellular carcinoma with the "wait and not ablate" approach until meeting T2 criteria for liver transplant listing.对于T1期肝细胞癌采用“等待且不消融”方法直至符合肝移植登记的T2标准的意向性治疗结果。
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