Swami H M, Thakur J S, Bhatia S P S
Department of Community Medicine, Government Medical College & Hospital, Chandigarh, India.
Indian J Pediatr. 2002 Aug;69(8):675-8. doi: 10.1007/BF02722703.
Main objectives were to assess the feasibility of linking vitamin A delivery with National Immunization Days (NIDs) and to see the impact on xerophthalmia.
An Intervention study of mass distribution of vitamin A solution was undertaken to control widespread xerophthalmia prevalent in children living in about 26 slums of Chandigarh in the year 2000. Two rounds of mass distribution of Vitamin A solution covering 27642 and 31762 children in 1-5 years of age in first and second rounds, respectively, were undertaken. The findings of second round and post evaluation after intervention are presented here. An additional team of two persons per pulse polio immunization (PPI) centre delivered age specific doses of vitamin A solution through 98 centres and operational problems were recorded. PPI staff provided the supervision and PPI tally sheets were used.
The programme achieved a vitamin A coverage rate of 99% in first round and 88% in second round. Only two parents refused vitamin A solution. No side effect or cases of toxicity due to vitamin A were reported by health institutions in the area or in a stratified random sample of 101 children. There was a significant decline (13.4%) in xerophthalmia after two rounds of mass distribution (P < .001). The strategy to deliver vitamin A was successfully integrated into NID's and appeared to achieve a significant decline in xerophthalmia.
Linking of vitamin A distribution with PPI could be a basis for launching similar initiatives in other areas of India and other countries where xerophthalmia is a public health problem.
主要目的是评估将维生素A发放与全国免疫日(NIDs)相结合的可行性,并观察其对干眼病的影响。
开展了一项维生素A溶液大规模分发的干预研究,以控制2000年在昌迪加尔约26个贫民窟生活的儿童中普遍存在的广泛干眼病。分别进行了两轮维生素A溶液大规模分发,第一轮覆盖1至5岁儿童27642名,第二轮覆盖31762名。本文介绍了第二轮的研究结果以及干预后的评估情况。每个脊髓灰质炎强化免疫(PPI)中心额外增加两人组成的团队,通过98个中心发放特定年龄段剂量的维生素A溶液,并记录操作问题。PPI工作人员进行监督,并使用PPI计数表。
该项目在第一轮的维生素A覆盖率为99%,第二轮为88%。只有两名家长拒绝接受维生素A溶液。该地区的卫生机构或在101名儿童的分层随机样本中,均未报告因维生素A产生的副作用或中毒病例。两轮大规模分发后,干眼病显著下降(13.4%)(P < .001)。发放维生素A的策略成功地融入了全国免疫日,并且似乎使干眼病显著下降。
将维生素A分发与脊髓灰质炎强化免疫相结合,可为印度其他地区以及干眼病成为公共卫生问题的其他国家开展类似举措提供依据。