Analgesia for paediatric tonsillectomy and adenoidectomy with intramuscular clonidine.
作者信息
Freeman Katherine O, Connelly Neil Roy, Schwartz Donald, Jacobs Barry R, Schreibstein Jerry M, Gibson Charles
机构信息
Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.
出版信息
Paediatr Anaesth. 2002 Sep;12(7):617-20. doi: 10.1046/j.1460-9592.2002.00914.x.
BACKGROUND
After undergoing tonsillectomy and adenoidectomy (T&A), children may experience significant pain. Clonidine, an alpha2 agonist, exhibits significant analgesic properties. The current investigation sought to determine whether intramuscular (I.M.) clonidine would decrease pain in paediatric patients undergoing T&A.
METHODS
Thirty-nine children undergoing elective T&A were studied. Following inhalational anaesthetic induction, fentanyl (2 microg x kg(-1)) was given intravenously, acetaminophen (paracetamol) (30 mg.kg-1) was given rectally and the children then randomly received an i.m. injection of either normal saline or clonidine (2 microg x kg(-1)). Perioperative analgesic requirements in the postanaesthesia care unit and at home following hospital discharge were evaluated.
RESULTS
There were no significant demographic, analgesic consumption, haemodynamic or pain score differences between the groups.
CONCLUSIONS
We do not recommend adding i.m. clonidine (2 microg x kg(-1)) to the analgesic regimen of children undergoing tonsillectomy and adenoidectomy.
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