Johnson Richard T, Irani David N
Department of Neurology, The Johns Hopkins Hospital, 600 North Wolfe Street, Pathology 627, Baltimore, MD 21287, USA.
Curr Neurol Neurosci Rep. 2002 Nov;2(6):496-500. doi: 10.1007/s11910-002-0035-0.
West Nile virus appeared in New York City in 1999 and has subsequently spread over the eastern United States. The mode of transport across the Atlantic Ocean is unknown. During the past decade, encephalitis has been a more prominent feature of West Nile virus infection in Europe, the Middle East, and the United States, suggesting the emergence of more neurovirulent strains. The rapid spread of the virus and more serious disease caused by the virus have spurred vaccine development.
西尼罗河病毒于1999年出现在纽约市，随后蔓延至美国东部。其跨大西洋的传播方式尚不清楚。在过去十年中，脑炎在欧洲、中东和美国已成为西尼罗河病毒感染更为突出的特征，这表明出现了更具神经毒性的毒株。该病毒的迅速传播以及由其引发的更严重疾病促使了疫苗的研发。
