Johnston J R, Isles K D, Muir D C
Inhaled Part. 1975 Sep;4 Pt 1:61-73.
This paper concerns the inertial deposition of aerosol particles in models of human branching airways. Homogeneous monodisperse aerosols of known characteristics were generated using a spinning disc atomizer. These were paused through simple bend systems of differing geometries, and the fractional deposition measured by a fluorimetric technique. The parameter characterizing 50 per cent deposition in the bend was found to agree with that predicted theoretically. Deposition in five models of bifurcating airways having geometries generally compatible with existing anatomical data was studied using essentially the same experimental procedure. The magnitude of the inertial deposit was measured and the overall effect of fluid-flow rate, particle size, branching angle and size of model determined. The results were compared with exsting theoretical estimates of impaction in a bifurcating airway.
本文关注人类支气管模型中气溶胶颗粒的惯性沉积。使用旋转盘式雾化器生成具有已知特性的均匀单分散气溶胶。这些气溶胶通过不同几何形状的简单弯曲系统,并用荧光技术测量分数沉积。发现表征弯曲处50%沉积的参数与理论预测值相符。使用基本相同的实验程序研究了五个具有与现有解剖学数据总体兼容的几何形状的分叉气道模型中的沉积。测量了惯性沉积物的大小,并确定了流体流速、颗粒大小、分支角度和模型尺寸的总体影响。将结果与分叉气道中现有撞击理论估计值进行了比较。