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优拓SSD:一种新型非黏附性脂质胶体敷料。

Urgotul: a novel non-adherent lipidocolloid dressing.

作者信息

Meaume S, Senet P, Dumas R, Carsin H, Pannier M, Bohbot S

机构信息

Geriatric Department, Hôpital Charles Foix, Ivry sue Seine, Paris, France.

出版信息

Br J Nurs. 2002 Sep;11(16 Suppl):S42-3, S46-50. doi: 10.12968/bjon.2002.11.Sup3.10556.

DOI:10.12968/bjon.2002.11.Sup3.10556
PMID:12362152
Abstract

Urgotul belongs to a new class of non-adherent dressings: the lipidocolloid dressings. It is composed of an open weave polyester mesh impregnated with hydrocolloid polymers dispersed within petrolatum. The first clinical trial data are presented. Efficacy and safety were evaluated in a multicentre non-comparative trial involving 92 patients treated to healing or up to 4 weeks. Adult outpatients with acute wounds (n = 34), leg ulcers (n = 24), other chronic wounds (n = 14) or with second-degree burns (n = 20) were included. Results showed 32.4% (n = 11) of the acute wounds, 12.5% (n = 3) of the leg ulcers and 14.3% (n = 2) of the other chronic wounds completely healed before 4 weeks. Surface areas decreased on average by 76.4%, 63.5% and 44.2% at study endpoint respectively. For burns, 19 patients healed (95%) within 5-19 days. A total of 771 dressing changes were performed during the course of the study. Dressing application was considered as easy or very easy in 90% or more of the changes and there was no difficulty in removing the dressing in about 95% of the cases. Safety was good with five reports of a transitory local adverse event, probably dressing-related, being observed, two patients (2.2%) prematurely stopped treatment because of moderate periwound erythema. Urgotul is a highly promising new dressing which is currently undergoing further comparative clinical evaluation.

摘要

优格托(Urgotul)属于一类新型的非粘性敷料:脂质胶体敷料。它由开放式编织聚酯网组成,该聚酯网浸渍有分散在凡士林内的水胶体聚合物。本文展示了首个临床试验数据。在一项多中心非对照试验中对其疗效和安全性进行了评估,该试验纳入了92例患者,治疗至伤口愈合或长达4周。纳入了患有急性伤口(n = 34)、腿部溃疡(n = 24)、其他慢性伤口(n = 14)或二度烧伤(n = 20)的成年门诊患者。结果显示,32.4%(n = 11)的急性伤口、12.5%(n = 3)的腿部溃疡和14.3%(n = 2)的其他慢性伤口在4周前完全愈合。在研究终点时,伤口表面积平均分别减少了76.4%、63.5%和44.2%。对于烧伤患者,19例(95%)在5 - 19天内愈合。在研究过程中总共进行了771次换药。在90%或更多的换药过程中,敷料的应用被认为容易或非常容易,并且在大约95%的病例中去除敷料没有困难。安全性良好,观察到5例短暂的局部不良事件报告,可能与敷料有关,2例患者(2.2%)因伤口周围中度红斑而提前停止治疗。优格托是一种非常有前景的新型敷料,目前正在进行进一步的对照临床评估。

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1
Urgotul: a novel non-adherent lipidocolloid dressing.优拓SSD:一种新型非黏附性脂质胶体敷料。
Br J Nurs. 2002 Sep;11(16 Suppl):S42-3, S46-50. doi: 10.12968/bjon.2002.11.Sup3.10556.
2
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Br J Nurs. 2007;16(6):S4, S6, S8 passim. doi: 10.12968/bjon.2007.16.Sup1.27088.
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Br J Nurs. 2004 Mar;13(6 Suppl):S20-8. doi: 10.12968/bjon.2004.13.Sup1.12536.
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Using Urgotul dressing for the management of epidermolysis bullosa skin lesions.使用优拓敷料治疗大疱性表皮松解症皮肤损伤。
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