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水胶体自粘性敷料在门诊治疗浅Ⅱ度烧伤中的益处。

Benefit of hydrocolloid SSD dressing in the outpatient management of partial thickness burns.

作者信息

Muangman Pornprom, Muangman Saipin, Opasanon Supaporn, Keorochana Kris, Chuntrasakul Chomchark

机构信息

Burn Unit, Trauma Division, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2009 Oct;92(10):1300-5.

Abstract

Silver sulfadiazine has been used as topical medication in the treatment of partial-thickness burns or secondary degree burns for many years. Pain during daily wound cleansing is the main problem. Urgotul SSD, a hydrocolloid dressing with silver sulfadiazine (SSD) has been reported to reduce infection and exhibit antimicrobial activity in burn wounds. The purpose of the present study was to compare the efficacy of Urgotul SSD and 1% silver sulfadiazine for treatment of partial thickness burn wounds. The authors reviewed 68 patients who had partial thickness burn wound less than 15% total body surface area (TBSA%) and were treated at Siriraj outpatient burn clinic during July 2005-December 2006. All patients were divided into two groups: Urgotul SSD treated group (34 patients) and 1% silver sulfadiazine treated group (34 patients). The two groups were compared by the demographic data including age, gender, % total body surface area (TBSA) burn, % TBSA deep burn, type of burn as well as percent of wound infection, total cost of wound dressing, pain medication, level of pain and time of wound healing. There were no differences in demographic data of age, % TBSA burn, % wound infection, total treatment cost of burn wound care (52 +/- 38 US$ for Urgotul SSD versus 45 +/- 34 US$ for silver sulfadiazine treated group). Time of wound closure was significantly shorter in the Urgotul SSD treated group (10 +/- 4 days in Urgotul SSD versus 12 +/- 6 in 1% silver sulfadiazine treated group) between both groups (p < 0.05). Average pain scores and pain medication in Urgotul SSD treated group was significantly lower than 1% silver sulfadiazine treated group (3 +/- 1 versus 6 +/- 2 and respectively, p < 0.05). All of the patients who developed wound infection responded well to targeted topical and oral antibiotic treatment. The authors conclude that Urgotul SSD has advantages of reducing pain symptom, pain medication requirement, increased patient convenience due to decreased time of follow-up at outpatient burn clinic, limiting the frequency of replacement of the dressing at comparable total cost and incidence of burn wound infection. The present study confirms the efficacy of Urgotul SSD in the treatment of partial thickness or secondary degree burn wound at the outpatient clinic.

摘要

多年来,磺胺嘧啶银一直被用作局部用药治疗浅Ⅱ度烧伤或二度烧伤。日常伤口清创时的疼痛是主要问题。据报道,含磺胺嘧啶银(SSD)的水胶体敷料优拓SSD可减少烧伤创面感染并具有抗菌活性。本研究的目的是比较优拓SSD和1%磺胺嘧啶银治疗浅Ⅱ度烧伤创面的疗效。作者回顾了2005年7月至2006年12月期间在诗里拉吉门诊烧伤诊所接受治疗、浅Ⅱ度烧伤创面面积小于体表面积(TBSA)15%的68例患者。所有患者分为两组:优拓SSD治疗组(34例患者)和1%磺胺嘧啶银治疗组(34例患者)。通过人口统计学数据对两组进行比较,包括年龄、性别、烧伤体表面积百分比(%TBSA)、深度烧伤体表面积百分比(%TBSA)、烧伤类型以及伤口感染百分比、伤口敷料总费用、止痛药物、疼痛程度和伤口愈合时间。年龄、%TBSA烧伤、伤口感染百分比、烧伤创面护理总治疗费用(优拓SSD组为52±38美元,磺胺嘧啶银治疗组为45±34美元)等人口统计学数据无差异。两组之间,优拓SSD治疗组的伤口愈合时间明显更短(优拓SSD组为10±4天,1%磺胺嘧啶银治疗组为12±6天)(p<0.05)。优拓SSD治疗组的平均疼痛评分和止痛药物使用量明显低于1%磺胺嘧啶银治疗组(分别为3±1和6±2,p<0.05)。所有发生伤口感染的患者对针对性的局部和口服抗生素治疗反应良好。作者得出结论,优拓SSD具有减轻疼痛症状、减少止痛药物需求、因减少门诊烧伤诊所随访时间而增加患者便利性、在总费用相当的情况下减少换药频率以及降低烧伤创面感染发生率等优点。本研究证实了优拓SSD在门诊治疗浅Ⅱ度或二度烧伤创面的疗效。

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