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Nitric oxide may contribute to the long-term impairment of synaptic transmission after transient ischemia.

作者信息

Mongin A A

出版信息

Stroke. 2002 Oct;33(10):2348-50; author reply 2348-50. doi: 10.1161/01.str.0000033074.40202.8e.

DOI:10.1161/01.str.0000033074.40202.8e
PMID:12364719
Abstract
摘要

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Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury.短暂性中度缺血性损伤后大脑皮质中递质释放和突触素磷酸化的持续性缺陷。
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Long-lasting inhibition of presynaptic metabolism and neurotransmitter release by protein S-nitrosylation.蛋白质 S-亚硝基化对突触前代谢和神经递质释放的持久抑制。
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