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多电极记录:下一步

Multielectrode recordings: the next steps.

作者信息

Nicolelis Miguel A L, Ribeiro Sidarta

机构信息

Department of Neurobiology, Box 3209, Duke University, Durham, North Carolina 27710, USA.

出版信息

Curr Opin Neurobiol. 2002 Oct;12(5):602-6. doi: 10.1016/s0959-4388(02)00374-4.

DOI:10.1016/s0959-4388(02)00374-4
PMID:12367642
Abstract

At present, a growing number of laboratories are acquiring the capability of simultaneously monitoring the extracellular activity of over a hundred single neurons in both anaesthetized and awake animals. This paradigm, known as multielectrode recordings, is changing the face of systems neuroscience by allowing, for the first time, the visualization of the function of entire neural circuits at work. Current methods of multielectrode recording employ state of the art technologies; two potential new avenues of research will likely emerge from the further development of these experimental paradigms.

摘要

目前,越来越多的实验室正在获得同时监测麻醉和清醒动物中一百多个单个神经元细胞外活动的能力。这种被称为多电极记录的模式正在改变系统神经科学的面貌,因为它首次使得观察整个工作中的神经回路的功能成为可能。当前的多电极记录方法采用了最先进的技术;这些实验模式的进一步发展可能会产生两条潜在的新研究途径。

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