Cope Jeffrey T, Fraser Gregory D, Kouretas Peter C, Kron Irving L
Department of Surgery, Division of Thoracic & Cardiovascular Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
Ann Surg. 2002 Oct;236(4):514-20; discussion 520-1. doi: 10.1097/00000658-200210000-00014.
To assess the authors' hypothesis that with modern techniques, the current risks of repair for both complete and partial atrioventricular canal (AVC) are equal.
Repair of complete AVC in infancy has traditionally carried a substantial mortality. In contrast, partial AVC has been considered low-risk for repair and can be performed later in childhood.
This was a retrospective review of 63 infants and children who underwent complete (n = 40) or partial AVC repair (n = 23) from 1990 to 2001. Among complete AVC patients, the ventriculoseptal defect was repaired via an individualized approach according to each patient's specific anatomy: direct suturing without a patch (n = 5) and/or interposition of a small pericardial patch with a running suture (n = 35). In all 63 patients the left AV valve cleft was closed with interrupted sutures, and all atrial defects were closed with a pericardial patch. Data were analyzed with the Student test and Fisher exact test.
Results are expressed as the mean +/- SEM. Age at operation was 6.3 +/- 2.0 months for complete AVC and 47.5 +/- 6.1 months for partial AVC (P <.001). Bypass time was 65.2 +/- 2.3 minutes for complete AVC and 58.3 +/- 3.9 minutes for partial AVC ( P=.1). Reoperation rate was 7.5% (3/40) for complete AVC and 13.0% (3/23) for partial AVC ( P=.6). Early mortality was 2.5% (1/40) for complete AVC and 0% (0/23) for partial AVC ( P=.6).
Compared to partial AVC, patients presenting for complete AVC repair are significantly younger and manifest more complex anatomy and pathophysiology. However, utilizing modern techniques, including an individualized surgical approach to the ventricular component, repair of complete AVC yields reoperation and early mortality rates similar to those of partial AVC.
评估作者的假设,即采用现代技术,完全性和部分性房室通道(AVC)修复的当前风险是相等的。
婴儿期完全性AVC修复传统上死亡率很高。相比之下,部分性AVC被认为修复风险低,可在儿童期后期进行。
这是一项对1990年至2001年间接受完全性(n = 40)或部分性AVC修复(n = 23)的63例婴儿和儿童的回顾性研究。在完全性AVC患者中,室间隔缺损根据每位患者的具体解剖结构采用个体化方法修复:直接缝合不使用补片(n = 5)和/或用连续缝合置入小的心包补片(n = 35)。在所有63例患者中,左房室瓣裂用间断缝合关闭,所有心房缺损用心包补片关闭。数据采用学生检验和Fisher精确检验进行分析。
结果以平均值±标准误表示。完全性AVC手术时年龄为6.3±2.0个月,部分性AVC为47.5±6.1个月(P <.001)。完全性AVC体外循环时间为65.2±2.3分钟,部分性AVC为58.3±3.9分钟(P =.1)。完全性AVC再次手术率为7.5%(3/40),部分性AVC为13.0%(3/23)(P =.6)。完全性AVC早期死亡率为2.5%(1/40),部分性AVC为0%(0/23)(P =.6)。
与部分性AVC相比,接受完全性AVC修复的患者年龄明显更小,解剖结构和病理生理更复杂。然而,采用现代技术,包括对心室部分采用个体化手术方法,完全性AVC修复的再次手术率和早期死亡率与部分性AVC相似。