Singh R Ramesh, Warren Patrick S, Reece T Brett, Ellman Peter, Peeler Benjamin B, Kron Irving L
Department of Surgery, University of Virginia, Charlottesville, Virginia 22908, USA.
Ann Thorac Surg. 2006 Nov;82(5):1598-601; discussion 1602. doi: 10.1016/j.athoracsur.2006.05.102.
Surgical repair of complete atrioventricular septal defect (CAVSD) is a well-established procedure performed on young children. Our hypothesis is that with modern techniques, the current risks of CAVSD repair in children aged younger than 3 months and in children older than 3 months are equal.
This was a retrospective review of 65 infants and children with a mean age of 10.9 months (range, 1 month to 15.5 years) who underwent CAVSD repair from 1990 to 2004. Twenty-six repairs (40%) were done on or before 3 months of age (group A) and 39 repairs (60%) were done after 3 months of age (group B). In all patients, the ventricular septal defect was repaired with an individualized approach according to each patient's specific anatomy: direct suturing without a patch, interposition of a small pericardial patch with a running suture, or both. The atrioventricular commissure was closed with interrupted sutures, and all atrial defects were closed with a pericardial patch. Data were analyzed using the chi2 analysis and the Fisher exact test.
Three hospital deaths occurred (<30 days), 2 in group A and 1 in group B (7.7% vs 2.6%, respectively, p = 0.33). One death in group A occurred during another noncardiac surgery. Early reoperation (<1 year of initial surgery) for residual ventricular septal defect or significant mitral regurgitation, or both, occurred in 3 group A patients and in 4 group B patients (11.5% versus 10.3% respectively, p = 0.68).
These results suggest that repair of CAVSD defects in children 3 months of age or younger had similar outcomes compared with those who underwent surgical repair after 3 months of age.
完全性房室间隔缺损(CAVSD)的外科修复是针对幼儿实施的一项成熟手术。我们的假设是,采用现代技术,3个月以下儿童和3个月以上儿童进行CAVSD修复的当前风险是相等的。
这是一项对1990年至2004年期间接受CAVSD修复的65例婴儿和儿童进行的回顾性研究,这些患者的平均年龄为10.9个月(范围为1个月至15.5岁)。26例修复手术(40%)在3个月龄及之前完成(A组),39例修复手术(60%)在3个月龄之后完成(B组)。对于所有患者,根据每位患者的具体解剖结构采用个体化方法修复室间隔缺损:直接缝合不使用补片、用连续缝合置入小的心包补片或两者结合。房室交界用间断缝合关闭,所有心房缺损用心包补片关闭。数据采用卡方分析和Fisher精确检验进行分析。
发生了3例院内死亡(<30天),A组2例,B组1例(分别为7.7%和2.6%,p = 0.33)。A组1例死亡发生在另一次非心脏手术期间。因残余室间隔缺损或严重二尖瓣反流或两者同时存在而进行的早期再次手术(初次手术后<1年),A组有3例患者,B组有4例患者(分别为11.5%和10.3%,p = 0.68)。
这些结果表明,3个月及以下儿童的CAVSD缺损修复与3个月以上接受手术修复的儿童相比,结果相似。