Bori Rita, Kiss Csaba Akos, Huszka Endre, Szûcs Miklós, Tusa Magdolna, Cserni Gábor
Pathologiai osztály, Bács-Kiskun Megyei Onkormányzat Kórháza, Kecskemét, 6000, Hungary.
Magy Onkol. 2002;46(3):261-4. Epub 2002 Oct 6.
To report a rare case of tumour-to-tumour metastasis with differential diagnostic considerations.
We report the operation of a Sylvian fissure secretory meningioma in a 48 year-old woman. The tumour was suspicious of a metastasis related to a pulmonary adenocarcinoma operated 4 months before. Histopathology confirmed metastatic adenocarcinoma in a secretory meningioma.
Both secretory meningioma and tumour-to-tumour metastasis are rare, and to our knowledge this is the first report of such a rare coincidence. Secretory meningioma can simulate metastases both clinically (extensive oedema, space occupation, carcinoembryonic antigen secretion) and pathologically (secretory inclusions, positivity for cytokeratin 7 and carcinoembryonic antigen and negativity for vimentin), and therefore may cause a special differential diagnostic dilemma.
报告一例罕见的肿瘤-to-肿瘤转移病例及鉴别诊断相关考量。
我们报告了一名48岁女性的外侧裂分泌性脑膜瘤手术情况。该肿瘤疑似与4个月前接受手术的肺腺癌转移有关。组织病理学证实分泌性脑膜瘤中存在转移性腺癌。
分泌性脑膜瘤和肿瘤-to-肿瘤转移均较为罕见，据我们所知，这是这种罕见巧合的首例报告。分泌性脑膜瘤在临床（广泛水肿、占位效应、癌胚抗原分泌）和病理（分泌性包涵体、细胞角蛋白7和癌胚抗原阳性、波形蛋白阴性）方面均可模拟转移，因此可能导致特殊的鉴别诊断困境。
