Ravnik Janez, Ravnik Maja, Bunc Gorazd, Glumbic Ivana, Tobi-Veres Erzebet, Velnar Tomaz
Department of Neurosurgery, University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia.
Department of Oncology, University Medical Centre Maribor, Ljubljanska 5, 2000, Maribor, Slovenia.
World J Surg Oncol. 2015 Oct 5;13:292. doi: 10.1186/s12957-015-0714-3.
Tumour-to-tumour metastasis is an infrequent pathological phenomenon. Meningioma is the most common intracranial tumour where metastatic deposits may be found, the majority of which arise from breast and lung cancers. We describe an unusual case of occult pulmonary carcinoma metastasis into the intracranial meningioma. A 77-year old lady presented with acutely deteriorating hemiparesis. Her previous medical history was unremarkable. Radiological imaging revealed an expansive lesion, classified as meningioma, which was located parasagittally in the right premotor area. A well-capsulated tumour attached to the dura was removed surgically. The pathological examination demonstrated a mixture of angiomatous meningioma and pulmonary adenocarcinoma. Possible explanations for the development of a composite tumour and pathophysiology are described.
肿瘤间转移是一种罕见的病理现象。脑膜瘤是颅内最常见的可发现转移灶的肿瘤,其中大多数转移灶源自乳腺癌和肺癌。我们描述了一例隐匿性肺癌转移至颅内脑膜瘤的罕见病例。一名77岁女性因急性加重的偏瘫就诊。她既往病史无特殊。影像学检查发现一个位于右侧运动前区矢状旁的占位性病变,分类为脑膜瘤。手术切除了一个与硬脑膜相连、包膜完整的肿瘤。病理检查显示为血管性脑膜瘤和肺腺癌的混合。文中描述了复合肿瘤形成的可能原因及病理生理学机制。