Reversal of enantioselectivity in the asymmetric rhodium- versus iridium-catalyzed hydroboration of meso substrates.
作者信息
Luna Alejandro Pérez, Bonin Martine, Micouin Laurent, Husson Henri-Philippe
机构信息
Laboratoire de Chimie Thérapeutique, UMR 8638 associée au CNRS et à l'Université René Descartes, Faculté des Sciences Pharmaceutiques et Biologiques, 4 av de l'Observatoire, 75270 Paris Cedex 06, France.
出版信息
J Am Chem Soc. 2002 Oct 16;124(41):12098-9. doi: 10.1021/ja026714m.
PMID:12371841
Abstract
The Ir-catalyzed asymmetric hydroboration of bicyclic hydrazines with ee and chemical yields up to 64% is reported. The switch from rhodium to iridium leads systematically to opposite enantiomers in this desymmetrization reaction.
摘要
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